HCV REPLICATION SYSTEM AND METHODS OF USE THEREOF

摘要

ABSTRACT OF THE DISCLOSUREThe present invention relates generally to methods of replicating hepatitis C virus (HCV) and, more specifically, to cultured human cells lines that can be infected with, and support the expression of, HCV genetic materials and production of HCV particles over many generations. The invention further relates to the use of such a cell culture system to identify agents useful in the prevention or treatment of HCV infections.