发明名称 |
METHOD FOR THE IDENTIFICATION OF LIGANDS |
摘要 |
The present invention relates generally to a method of identifying ligands that modulate protein-protein interactions. More particularly, the present invention relates to methods of determining agonists or antagonists of a co- regulator dependent target molecule based on the ability to modify the stability of the target molecule.
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申请公布号 |
CA2491345(A1) |
申请公布日期 |
2004.01.29 |
申请号 |
CA20022491345 |
申请日期 |
2002.09.20 |
申请人 |
3-DIMENSIONAL PHARMACEUTICALS, INC. |
发明人 |
ASKARI, HOSSEIN;SPRINGER, BARRY A.;RENTZEPERIS, DIONISIOS;SALEMME, FRANCIS R.;BONE, ROGER F. |
分类号 |
G01N33/50;C12Q1/48;C40B30/04;G01N33/15;G01N33/68;(IPC1-7):G01N33/53;A61K38/00;C07K1/00;C07K2/00;C07K4/00;C07K5/00;C07K7/00;C07K14/00;C07K16/00;C07K17/00;G01N33/567 |
主分类号 |
G01N33/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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