| 发明名称 |
METHODS AND COMPOSITIONS RELATING TO CHIMERIC NICOTINIC RECEPTOR SUBUNITS |
| 摘要 |
A chimeric nAChR receptor subunit polypeptide having a substitution of at least about 15% of the native amino acid sequence of the subunit in the area of the C-terminal cytoplasmic domain is provided, as well as polynucleotides encoding the polypeptide. Vectors, host cells, and related methods for evaluating compounds are also provided. |
| 申请公布号 |
WO2004009775(A2) |
申请公布日期 |
2004.01.29 |
| 申请号 |
WO2003US22550 |
申请日期 |
2003.07.18 |
| 申请人 |
TARGACEPT, INC.;CATHOLIC HEALTHCARE WEST;BENCHERIF, MEROUANE;LUKAS, RONALD, J. |
发明人 |
BENCHERIF, MEROUANE;LUKAS, RONALD, J. |
| 分类号 |
C07H21/04;C07K14/705;C12N15/09;C12P21/06 |
主分类号 |
C07H21/04 |
| 代理机构 |
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