The present invention provides compounds of formula I and pharmaceutically acceptable salts thereof. The formula I compounds inhibit tyrosine kinase activity of growth factor receptors such as HER1, HER2 and HER4 thereby making them useful as antiproliferative agents. The formula I compounds are also useful for the treatment of other diseases associated with signal transduction pathways operating through growth factor receptors.
申请公布号
WO03042172(A3)
申请公布日期
2004.01.29
申请号
WO2002US36528
申请日期
2002.11.12
申请人
BRISTOL-MYERS SQUIBB COMPANY;MASTALERZ, HAROLD;ZHANG, GUIFEN;TARRANT, JAMES, G.;VITE, GREGORY, D.
发明人
MASTALERZ, HAROLD;ZHANG, GUIFEN;TARRANT, JAMES, G.;VITE, GREGORY, D.