发明名称 ORALLY DELIVERABLE PHARMACEUTICAL COMPOSITION COMPRISING A DRUG OF LOW WATER SOLUBILITY (COX-2 INHIBITOR), A SOLVENT, A FATTY ACID AND AN ORGANIC AMINE.
摘要 <p>An orally deliverable pharmaceutical composition is provided comprising a drug of low water solubility and a solvent liquid that comprises at least one pharmaceutically acceptable solvent, at least one pharmaceutically acceptable fatty acid and at least one pharmaceutically acceptable organic amine, wherein (a) a substantial portion, for example at least about 15% by weight, of the drug is in dissolved or solubilized form in the solvent liquid, and (b) the fatty acid and the organic amine are present in total and relative amounts such that the composition is finely self-emulsifiable in simulated gastric fluid.</p>
申请公布号 MXPA03009411(A) 申请公布日期 2004.01.29
申请号 MX2003PA09411 申请日期 2002.04.12
申请人 PHARMACIA CORPORATION 发明人 AZIZ KARIM
分类号 C07D231/12;A61K9/08;A61K9/107;A61K9/48;A61K31/00;A61K31/415;A61K31/42;A61K31/52;A61K31/63;A61K31/635;A61K45/00;A61K47/12;A61K47/18;A61K47/34;A61P9/00;A61P25/06;A61P29/00;C07D261/08;(IPC1-7):A61K31/415;A61K47/10 主分类号 C07D231/12
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