PROTEIN COMPLEXES OF CELLULAR NETWORKS UNDERLYING THE DEVELOPMENT OF CANCER AND OTHER DISEASES

摘要

The present invention relates to protein complexes involved in cellular processes which have been shown to be critical for the development of various forms of cancer, component proteins of the said complexes, fragments and derivatives of the component proteins, and antibodies specific to the complexes. The present invention also relates to methods for use of the complexes and their interacting proteins in, inter alia, screening, diagnosis, and therapy, as well as to methods of preparing the complexes.