发明名称 |
Bioanalysis system and method using probe arrays |
摘要 |
A bioanalytic method (AP1) replenishes depleted zones in a sample liquid (161, 162, 163) in a shallow probe-array reaction cell (101, 102, 103) under ultragravity centrifugal forces. The ultragravity overcomes viscous and surface-tension forces to permit replenishment despite a shallow reaction-cell depth of 25 microns. Thus, replenishment is achieved using 1/10<th> the sample volume normally used in probe-array systems that use mixing to facilitate binding reactions. For similar amounts of sample, the shallow cell takes advantage of a ten-times greater concentration to achieve much greater signal strengths in much shorter times. Thus, signal strengths that normally take 17 hours to achieve are achieved in about 60 minutes. <IMAGE> |
申请公布号 |
EP1365015(A3) |
申请公布日期 |
2004.01.28 |
申请号 |
EP20030252900 |
申请日期 |
2003.05.09 |
申请人 |
AGILENT TECHNOLOGIES, INC. |
发明人 |
GORDON, GARY B.;OSTROWSKI, MAGDALENA ANNA |
分类号 |
B01F13/00;B01F15/02;B01L3/00;(IPC1-7):B01L3/00 |
主分类号 |
B01F13/00 |
代理机构 |
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代理人 |
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地址 |
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