发明名称 |
Fluorescent hybridization probes with reduced background |
摘要 |
The invention is directed to a pair of FRET hybridization probes consisting of a first oligonucleotide carrying a FRET donor entity and a second oligonucleotide carrying a FRET acceptor entity, wherein said first oligonucleotide carrying the donor fluorescent entity is carrying at least one second entity, said second entity being a compound which is capable of quenching fluorescence emission of said donor fluorescent entity. In addition, the invention is directed to methods of using the same.
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申请公布号 |
EP1384789(A1) |
申请公布日期 |
2004.01.28 |
申请号 |
EP20030016378 |
申请日期 |
2003.07.19 |
申请人 |
ROCHE DIAGNOSTICS GMBH;F.HOFFMANN-LA ROCHE AG |
发明人 |
HEINDL, DIETER, DR.;JOSEL, HANS-PETER, DR.;SAGNER, GREGOR, DR.;MAYR, JUTTA, DR. |
分类号 |
G01N33/53;C12N15/09;C12Q1/68;G01N33/566;G01N33/58;G01N37/00;(IPC1-7):C12Q1/68 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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