发明名称 DIPHENYL COMPOUNDS WHICH INHIBIT ARACHIDONIC ACID METABOLISM, AND THEIR USE IN PHARMACEUTICAL COMPOSITIONS
摘要 Pharmaceutical compositions, which comprise a compound of the general formul a I (see formula I) in which X is oxygen, sulfur or -CH2-, Y is chlorine or bromine, Z is an SO2 H, NO2 or C1-C4alkyl radical, r is a number from 0 to 3, o is a number from 0 to 3, p is the number 0 or 1, m is the number 1 or 2 and n is the number 0 or 1, have having a lipoxygenase- and prostaglandin H synthase-inhibiting action. The compositions are useful in particular for the local (topical) or inhalative treatment of inflammatory, allergic and spasmolytic diseases, as well as psoriasis, bronchial asthma and diseases with disturbances in cell proliferation.
申请公布号 CA2050569(C) 申请公布日期 2004.01.27
申请号 CA19912050569 申请日期 1991.09.03
申请人 CIBA-GEIGY AG 发明人 SCHEWE, TANKRED;LUTHER, HELMUT;JORDANOV, DENTSCHO
分类号 A61K31/01;A61K31/047;A61K31/05;A61K31/055;A61K31/06;A61K31/085;A61K31/10;A61K31/185;A61P1/00;A61P11/00;A61P11/06;A61P17/00;A61P17/06;A61P25/08;A61P29/00;A61P31/04;A61P37/08;A61P43/00;C07C39/367;C07C43/295;C07C205/22;C07C205/38;(IPC1-7):A61K31/05 主分类号 A61K31/01
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