| 发明名称 |
ADENOVIRUS-RECOMBINANT CARRYING ADENOVIRAL VECTOR STRUCTURE (VARIANTS), METHOD FOR RECOVERY FUNCTION OF PROTEIN P53 IN TUMOR CELL WITH DEFICIENCY OF NATURAL P53, METHOD FOR PRODUCING ADENOVIRUS-RECOMBINANT |
| 摘要 |
FIELD: genetic engineering, virology, medicine, oncology. SUBSTANCE: invention proposes adenovirus-recombinant comprising adenoviral vector that contains the natural gene p53 expressing protein p53 in mammalian cells. Effect of enhancement of protein p53 level in body is used in method for recovery function of protein p53 in tumor cell. Invention provides prophylaxis of tumor cells growth. EFFECT: valuable medicinal properties of adenovirus-recombinant. 34 cl, 24 dwg, 2 tbl, 7 ex |
| 申请公布号 |
RU2222600(C2) |
申请公布日期 |
2004.01.27 |
| 申请号 |
RU19960110223 |
申请日期 |
1994.10.28 |
| 申请人 |
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发明人 |
SHANG UEHJ-UEHJ;ROT DZHEK A. |
| 分类号 |
C12N15/09;A61K9/127;A61K35/76;A61K38/00;A61K38/17;A61K38/22;A61K48/00;A61P35/00;A61P35/04;A61P43/00;C07K14/47;C07K14/82;C12N5/10;C12N7/00;C12N15/11;C12N15/12;C12N15/33;C12N15/86;C12N15/861 |
主分类号 |
C12N15/09 |
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代理人 |
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| 主权项 |
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| 地址 |
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