STRAIN OF BACTERIUM ESCHERICHIA COLI = 2809:K99 USED FOR PREPARING VACCINE AND DIAGNOSTIC PREPARATION

摘要

FIELD: veterinary microbiology. SUBSTANCE: strain is agglutinated with sera: "O"-coli 09 and anti-adhesive K99 by serological properties. Strain produces thermostable enterotoxin. Virulence. Value LD50 for white mice in intraperitoneal administration is 1.2 x 108 living bacterial cells. Antigenic activity. Administration of antigen to animal body results to producing antitoxic and humoral immunity. Concentration of bacterial cells in culturing the strain is 50-60 billion. Strain is useful for preparing coli-bacteritic vaccines, diagnostica, for preparing hyperimmune curative sera and globulins. EFFECT: valuable properties of strain. 1 ex