发明名称 |
Antisense modulation of hmg-coa reductase expression |
摘要 |
<p>Antisense compounds, compositions and methods are provided for modulating the expression of HMG-CoA reductase. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding HMG-CoA reductase. Methods of using these compounds for modulation of HMG-CoA reductase expression and for treatment of diseases associated with expression of HMG-CoA reductase are provided.</p> |
申请公布号 |
AU2003281324(A8) |
申请公布日期 |
2004.01.23 |
申请号 |
AU20030281324 |
申请日期 |
2003.07.02 |
申请人 |
ISIS PHARMACEUTICALS INC. |
发明人 |
KENNETH W. DOBIE;NICHOLAS M. DEAN;SUSAN M. FREIER |
分类号 |
A61K38/00;C07H21/04;C12N5/02;C12N15/113;(IPC1-7):C12Q1/68;C12P19/34;A01N43/04;C12N15/63;C07H21/02 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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