发明名称 |
Transdermal pharmaceutical delivery composition |
摘要 |
A pharmaceutically delivery system is described comprising a pharmaceutically active agent and acidified nitrite as an agent to produce local production of nitric oxide at the skin surface. The dosage form may be in any pharmaceutically acceptable carrier means and comprises an acidifying agent adapted to reduce the pH at the environment. In one embodiment, a barrier consisting of a membrane allows diffusions of the anaesthetic and nitrite ions while preventing direct contact of the skin and acidifying agent.
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申请公布号 |
US2004013747(A1) |
申请公布日期 |
2004.01.22 |
申请号 |
US20030363439 |
申请日期 |
2003.06.16 |
申请人 |
TUCKER ARTHUR T.;BENJAMIN NIGEL |
发明人 |
TUCKER ARTHUR T.;BENJAMIN NIGEL |
分类号 |
A61K47/04;A61K9/06;A61K31/167;A61K31/245;A61K31/445;A61K47/02;A61K47/12;A61K47/22;A61P5/00;A61P5/38;A61P23/02;A61P29/00;A61P37/06;(IPC1-7):A61K33/00;A61K31/56;A61K31/60;A61K31/375 |
主分类号 |
A61K47/04 |
代理机构 |
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代理人 |
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地址 |
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