Use of microsomal triglyceride transfer protein (mtp) inhibitors for reducing the number of postprandiatriglyceride-rich lipoprotein particles (pptrl)

摘要

The invention relates to the use of inhibitors of the microsomal triglyceride transfer protein (MTP) for reducing the number of postprandial triglyceride-rich lipoprotein particles (ppTRL) or for reducing their decomposition products i.e. the cholestcrol-rich "small remnant particle" (remnants). Said particles are associated with apolipoprotein B-48 (ApoB-48) and are designated as "ppTRL" in the further course of events.