发明名称 |
SUBSTITUTED BENZYLAMINE DERIVATIVES AND METHODS OF USE |
摘要 |
Selected compounds of formula IV are effective for prophylaxis and treatment of diseases, such as angiogenesis mediated diseases. The invention encompass es novel compounds, analogs, prodrugs and pharmaceutically acceptable derivativ es thereof, pharmaceutical compositions and methods for prophylaxis and treatme nt of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as intermediates useful in such processes (IV).
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申请公布号 |
CA2492164(A1) |
申请公布日期 |
2004.01.22 |
申请号 |
CA20032492164 |
申请日期 |
2003.07.15 |
申请人 |
AMGEN INC. |
发明人 |
NISHIMURA, NOBUKO;LI, AIWEN;YUAN, CHESTER CHENGUANG;PATEL, VINOD F.;KIM, JOSEPH L.;ASKEW, BENNY C., JR.;BOOKER, SHON;GERMAIN, JULIE;KIM, TAE-SEONG;HABGOOD, GREGORY;HANDLEY, MICHAEL;ELBAUM, DANIEL |
分类号 |
A61K31/44;A61K31/4427;A61K31/443;A61K31/4436;A61K31/4439;A61K31/444;A61K31/4709;A61K31/4725;A61K31/496;A61K31/498;A61K31/501;A61K31/506;A61K31/517;A61K31/5377;A61K31/538;A61P1/04;A61P3/00;A61P3/04;A61P3/10;A61P9/00;A61P9/10;A61P11/00;A61P11/06;A61P15/00;A61P15/08;A61P17/00;A61P17/02;A61P17/06;A61P19/00;A61P19/02;A61P21/00;A61P25/28;A61P27/02;A61P27/06;A61P29/00;A61P31/12;A61P31/18;A61P31/22;A61P35/00;A61P35/02;A61P35/04;A61P37/02;A61P37/04;A61P37/08;A61P43/00;C07D213/81;C07D213/82;C07D237/04;C07D237/24;C07D401/12;C07D401/14;C07D405/12;C07D409/12;C07D413/12;C07D413/14;C07D417/12;C07D471/04;(IPC1-7):C07D213/81;C07D407/12;A61K31/442;A61K31/454 |
主分类号 |
A61K31/44 |
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