发明名称 |
Process for the preparation of citalopram |
摘要 |
Preparation of citalopram comprises the steps of: (a) converting the compound of Formula (I) to a compound of Formula (II), wherein R in Formula (I) represents a C2 to C5 alkylene group which may be substituted or unsubstituted, and R<1 >in the compounds of Formula (II) represents a carboxylic acid group or a salt or an ester thereof; and (b) converting the compound of Formula (II) to form citalopram or a pharmaceutically acceptable salt thereof, or a direct conversion of the compound of Formula (I) to citalopram
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申请公布号 |
US2004014997(A1) |
申请公布日期 |
2004.01.22 |
申请号 |
US20020221012 |
申请日期 |
2002.12.16 |
申请人 |
GREENWOOD ALAN KENNETH;MCHATTIE DEREK;RECHKA JOSEF A.;HEDGER PAUL C.M.;GAMBLE MARK P. |
发明人 |
GREENWOOD ALAN KENNETH;MCHATTIE DEREK;RECHKA JOSEF A.;HEDGER PAUL C.M.;GAMBLE MARK P. |
分类号 |
C07D263/14;C07D307/87;(IPC1-7):C07D307/87 |
主分类号 |
C07D263/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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