发明名称 |
Process for producing medicinal solid dispersion |
摘要 |
It is a primary object of the present invention to provide a process for producing a pharmaceutical solid dispersion using a twin-screw compounding extruder, the pharmaceutical solid dispersion including hydroxypropyl methylcellulose as a carrier which is superior in elution property of pharmaceutical ingredients and in stability and the pharmaceutical solid dispersion being satisfactory for subsequent pharmaceutical preparations. The present invention is a process for producing a pharmaceutical solid dispersion including hydroxypropyl methylcellulose as a carrier with the use of a twin-screw compounding extruder, characterized in that a sugar alcohol is added as one of processing materials and kneading and extruding processes are performed for the processing materials with the use of the twin-screw compounding extruder.
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申请公布号 |
US2004013736(A1) |
申请公布日期 |
2004.01.22 |
申请号 |
US20030381173 |
申请日期 |
2003.03.20 |
申请人 |
NAKANO TOMIO;TANAKA TOSHINORI;IZUMI SHOGO |
发明人 |
NAKANO TOMIO;TANAKA TOSHINORI;IZUMI SHOGO |
分类号 |
A61K9/14;A61K9/16;(IPC1-7):A61K9/14 |
主分类号 |
A61K9/14 |
代理机构 |
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主权项 |
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地址 |
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