Method and system useful for structural classification of unknown polypeptides

摘要

A method of identifying a polypeptide candidate most likely to have undefined structural/functional elements is provided. The method is effected by (a) classifying each cluster of a database of non-structurally clustered polypeptide clusters as: (i) a first cluster, if it includes at least one structurally defined polypeptide; or (ii) a second cluster, if it is devoid of structurally defined polypeptides; (b) determining relational distances between at least one first cluster and a plurality of distinct second clusters according to at least one criteria; and (c) identifying second clusters of the plurality of distinct second clusters which exhibit a relational distance from the at least one first cluster which is greater than a predetermined threshold, thereby identifying the polypeptide candidate most likely to have undefined structural/functional elements.