发明名称 Use of carp inhibitors for the treatment of heart diseases
摘要 The present invention relates to the novel finding that inhibition of human CARP protein or of CARP DNA/mRNA may successfully cure heart disorders, especially heart failure in humans. The invention relates, therefore, to pharmaceutical compositions containing substances, preferably of lower molecular weight, which may influence the activity of cardiac CARP. The invention relates, furthermore, to a method of treatment heart failure using CARP inhibitory compounds, to methods for screening these inhibitors and to the use of CARP as diagnostic tool.
申请公布号 US2004014706(A1) 申请公布日期 2004.01.22
申请号 US20030363903 申请日期 2003.08.07
申请人 KLUXEN FRANZ-WERNER;HENTSCH BERND;WILM CLAUDIA;BRAENDLE MARIAN;ESCHENHAGEN THOMAS;ESCHENHAGEN THOMAS;ZOLK OLIVER 发明人 KLUXEN FRANZ-WERNER;HENTSCH BERND;WILM CLAUDIA;BRAENDLE MARIAN;ESCHENHAGEN THOMAS;ESCHENHAGEN THOMAS;ZOLK OLIVER
分类号 G01N33/50;A61K31/145;A61K45/00;A61K49/00;A61P9/00;A61P9/04;A61P43/00;C12N15/09;C12Q1/02;C12Q1/68;G01N33/15;G01N33/53;G01N33/566;(IPC1-7):A61K48/00 主分类号 G01N33/50
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