发明名称 |
Method for granulation of active substances by low pressure extrusion to obtain directly compressible granules |
摘要 |
The invention concerns a method for formulating one or several active substance(s) in the form of directly compressible granules comprising wet process granulation using a binding solution of said active substance and optionally associated excipients, then drying the resulting granules. The invention is characterised in that said granulation is carried out by low pressure extrusion of the mixture of the active substance(s), binding solution and optionally excipient(s).
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申请公布号 |
US2004013735(A1) |
申请公布日期 |
2004.01.22 |
申请号 |
US20030380954 |
申请日期 |
2003.07.30 |
申请人 |
MARTIN-LETELLIER STEPHAN;LE THIESSE JEAN-CLAUDE |
发明人 |
MARTIN-LETELLIER STEPHAN;LE THIESSE JEAN-CLAUDE |
分类号 |
A61K9/16;A61K9/20;(IPC1-7):A61K9/14;B27N3/00 |
主分类号 |
A61K9/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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