发明名称 Tropane derivatives useful in therapy
摘要 The present invention provides compounds of formula (I) wherein X, Y, R<1>, R<2 >and R<3 >are as defined hereinabove. The compounds of the present invention are modulators, especially antagonists, of the activity of chemokine CCR5 receptors. Modulators of the CCR5 receptor may be useful in the treatment of various inflammatory diseases and conditions, and in the treatment of infection by HIV and genetically related retroviruses.
申请公布号 US2004014742(A1) 申请公布日期 2004.01.22
申请号 US20030408856 申请日期 2003.04.07
申请人 发明人 BASFORD PATRICIA ANN;STEPHENSON PETER THOMAS;TAYLOR STEFAN COLIN JOHN;WOOD ANTHONY
分类号 A61P31/18;C07D519/00;(IPC1-7):C07D471/02;A61K31/55;A61K31/541;A61K31/537;A61K31/496;A61K31/474 主分类号 A61P31/18
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