A method for preparing a human or animal tissue by applying a compressive force to a stack of sheets of living tissue thereby inducing adjacent layers to fuse or adhere to each other. The force is applied in direction normal to the surface of the tissue. A multi-layer tissue produced by the method decribed above can also possess at least two different types of sheets and/or consist essentially of between two and twelve sheets of living tissue. The method can also be used to prepare a planar tissue that can further be incorporated in a multi-layer tissue construct. The methods and tissues described herein are useful for the preparation of engineered tissues.
申请公布号
WO2004007699(A2)
申请公布日期
2004.01.22
申请号
WO2003CA01079
申请日期
2003.07.16
申请人
ALTERTEK BIO INC.;GERMAIN, LUCIE;AUGER, FRANCOIS;BERGERON, FRANCOIS;ROBERGE, CHARLES
发明人
GERMAIN, LUCIE;AUGER, FRANCOIS;BERGERON, FRANCOIS;ROBERGE, CHARLES