发明名称 Vascular Endothelial Growth Factor Related Protein (VRP) Antagonists
摘要 <p>A human VEGF-related protein (VRP) has been identified and isolated that binds to, and stimulates the phosphorylation of, the receptor tyrosine kinase Flt4. The VRP is postulated to be a third member of the VEGF protein family. Also provided are antibodies that bind to VRP and neutralize a biological activity of VRP, compositions containing the VRP or antibody, methods of use, chimeric polypeptides, and a signal polypeptide for VRP. &lt;IMAGE&gt;</p>
申请公布号 EP1382679(A2) 申请公布日期 2004.01.21
申请号 EP20030011317 申请日期 1996.08.30
申请人 GENENTECH, INC. 发明人 LEE, JAMES;WOOD, WILLIAM
分类号 C07K14/71;G01N33/53;A61K31/00;A61K38/00;A61K48/00;A61P9/00;A61P17/00;A61P17/02;C07K14/52;C07K16/22;C07K16/24;C07K19/00;C12N5/00;C12N15/00;C12N15/19;C12P21/02;C12R1/91;G01N33/577;(IPC1-7):C12N15/19;C07K14/715;G01N33/50;A61K38/19 主分类号 C07K14/71
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