发明名称 |
SCREENING METHOD |
摘要 |
<p>A method for screening a compound acting on a bone or its salt characterized by using NRH: quinone oxidoreductase (NQO2), its peptide fragment or a salt thereof; agents acting on a bone comprising compounds obtained by the above method; a method of preventing/treating human or mammalian bone diseases involving the inhibition or promotion of the expression or activity of NQO2; and diagnostics for bone diseases containing a polynucleotide encoding NQO2 or its peptide fragment or an antibody having an affinity specifically for NQO2, its peptide fragment or a salt thereof.</p> |
申请公布号 |
EP1382688(A1) |
申请公布日期 |
2004.01.21 |
申请号 |
EP20020722727 |
申请日期 |
2002.04.24 |
申请人 |
TAKEDA CHEMICAL INDUSTRIES, LTD. |
发明人 |
TANI, AKIYOSHI;HONDA, SUSUMU;YASUMA, TSUNEO |
分类号 |
A61K38/00;A61K39/395;A61K48/00;A61P19/00;A61P19/08;A61P19/10;C07K16/00;C12N15/53;C12Q1/26;G01N33/68;(IPC1-7):C12Q1/26;A61K35/32 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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