| 摘要 |
FIELD: medicine, narcology, pharmacy. SUBSTANCE: invention relates to agent used for treatment of opiomania. Medicinal agent consists of antagonists of opiate receptors and pharmaceutically acceptable carrier. As antagonists of opiate receptors esters of N-substituted 14-hydroxy- morphinans are used; as a carrier natural oils, esters of carboxylic acid with 8-16 carbon atoms and low-molecular alcohols are used, sulfolanes, propylene carbonate, N,N- dimethylacetamide or their mixture are used taken in the definite ratio of components. Invention provides the development of highly effective low toxic an antirelapse agent with prolonged opioprotective effect being after a single subcutaneous or intramuscular injection. EFFECT: enhanced effectiveness of agent, valuable medicinal properties. 4 cl, 3 tbl |
