| 摘要 |
FIELD: organic chemistry, medicine, pharmacy. SUBSTANCE: invention relates to derivatives of tetrahydroisoquinoline alkanol of the formula (I) wherein X1 and X2 are hydrogen, halogen atom, alkoxy-group or nitro-group; Y is oxygen or sulfur atom; R1 is hydrogen atom, alkyl, phenylalkyl or CONHR' wherein R' is phenyl; R2 and R3 are similar or different of one another and are taken independently among group consisting of hydrogen atom and alkyl; R4 is hydrogen atom or lower alkyl. Also, invention describes pharmaceutical composition and methods for treatment of central nervous system disorders and depression. Invention provides preparing new compounds eliciting valuable biological properties. EFFECT: improved treatment method, valuable medicinal properties of compounds. 55 cl, 1 tbl, 22 ex |
