| 摘要 |
FIELD: biochemistry, labeled compounds. SUBSTANCE: invention relates to method for radioactive labeling proteins with therapeutic radioactive isotope for administration to patient. Method involves mixing protein or peptide conjugated with chelating agent with solution containing radioactive isotope or its salts, acceptable buffer, incubation for sufficient time at acceptable pH value and temperature that provides preparing the end product with radiochemical purity above 95%, sufficient specific activity and specificity binding at least about 50%. Prepared product can be administrated to patient without additional purification. Invention relates also to a set for realization of method representing flask containing protein or peptide conjugated with chelating agent in acceptable buffer, flask containing the composition buffer for stabilization and administration of radiolabeled protein or peptide to patient and instruction for carrying out procedure of radioactive labeling. EFFECT: improved labeling method. 50 cl, 8 tbl, 2 dwg, 3 ex
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