发明名称 |
FLOW IMMUNOSENSOR METHOD AND APPARATUS |
摘要 |
A method of detecting a target moiety comprising the steps of (a) providing an antibody (37) specific to the target, (b) satu- rating the antibody's (37's) binding sites with a labelled form of the targe t (39), (c) flowing a liquid containing the target past the antibody (37), (d) allowing the target to displace the labelled antigen (39) , and (e) detecting the displaced, labelled antigen (39). The invention is accomplished by a flow immunosensor: a flowing liquid moves a sample through the immunosensor; a receiving means (13) introduces the sample to the liquid; a flow control means (21, 23 ) controls the liquid's movement through the immu- nosensor; and exchanger (35) brings the sample into contact with labelled antigens of the target so that any target present dis- places the labelled antigen (39); a detection apparatus (41, 41a) detects an y labelled antigen (39) that is released; and a disposal means (45) disposes of or collects the waste coming from the detection apparatus (41, 41a).
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申请公布号 |
CA2076748(C) |
申请公布日期 |
2004.01.20 |
申请号 |
CA19912076748 |
申请日期 |
1991.02.21 |
申请人 |
THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SE CRE |
发明人 |
LIGLER, FRANCES S.;GABER, BRUCE P.;KUSTERBECK, ANNE W.;WEMHOFF, GREGORY A. |
分类号 |
G01N33/536;G01N33/53;G01N33/543;G01N35/02;(IPC1-7):G01N33/53 |
主分类号 |
G01N33/536 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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