SECRETED POLYPEPTIDE SPECIES ASSOCIATED WITH CARDIOVASCULAR DISORDERS

摘要

The invention provides novel human secreted polypeptides comprising an amino acid sequence of SEQ ID NOS. I-10. The polypeptides of the invention circulate at an elevated level in the plasma of patients with cardiovascular disorders. The invention also provides compositions including the polypeptides, polynucleotides encoding them, and antibodies specific for these polypeptides. Also provided are methods for making such compositions, and methods of using the compositions of the invention for diagnosis, prognosis, and treatment of cardiovascular disorders.