发明名称 |
REPLACING LIVER CELLS WITH BONE MARROW-DERIVED CELLS FOR TREATING DISEASE AND EXPRESSING THERAPEUTIC GENES |
摘要 |
The invention provides a method for introducing a population of Kupffer cells into an individual. The method includes the steps of (a) administering to an individual a Kupffer cell toxin, wherein the toxin ablates a first population of Kupffer cells of the individual, and (b) administering to the individual a population of Kupffer cell progenitors, wherein the population of Kupffer cell progenitors replaces the first population of Kupffer cells, thereby providing a second population of Kupffer cells. |
申请公布号 |
WO2004005488(A2) |
申请公布日期 |
2004.01.15 |
申请号 |
WO2003US21609 |
申请日期 |
2003.07.09 |
申请人 |
SAN DIEGO STATE UNIVERSITY FOUNDATION;DAVIS, ROGER, A. |
发明人 |
DAVIS, ROGER, A. |
分类号 |
A61K35/12;A61K48/00;C12N5/0789 |
主分类号 |
A61K35/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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