发明名称 |
Multi-dimensional fluorescence apparatus and method for rapid and highly sensitive quantitative analysis of mixtures |
摘要 |
Apparatus and methods are provided for rapid and sensitive quantitative analysis of a sample's fluorescence decay properties. A repetitively pulsed excitation light source generates pulsed fluorescence in the sample. A fluorescence wavelength selector receives a portion of the pulsed fluorescence emanating from the sample and outputs fluorescence photons whose wavelengths lie within a specified wavelength range. A photodetector receives the fluorescence photons within the specified wavelength range as an input from the fluorescence wavelength selector and outputs a time-dependent electrical signal. An array of memory elements stores a representation of the time-dependent electrical signal as a time-series of analog voltages or charges. Successive elements in the array correspond to a time increment of no greater than 4 ns. An analog-to-digital converter transforms the time-series of analog voltages or charges into a corresponding digitized fluorescence waveform.
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申请公布号 |
US2004007675(A1) |
申请公布日期 |
2004.01.15 |
申请号 |
US20030431347 |
申请日期 |
2003.05.07 |
申请人 |
GILLISPIE GREGORY;PAVICIC MARK J. |
发明人 |
GILLISPIE GREGORY;PAVICIC MARK J. |
分类号 |
G01J3/44;G01N;G01N21/64;(IPC1-7):G01N21/64 |
主分类号 |
G01J3/44 |
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地址 |
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