| 发明名称 |
2, 5-SUBSTITUTED PYRIMIDINE DERIVATIVES AS CCR-3 RECEPTOR ANTAGONISTS IX |
| 摘要 |
This invention relates to pyrimidine derivatives of Formula (I), wherein Ar1 , Ar2, R1-R5, X, Z and alk are as defined in the specification. The compounds are useful as CCR-3 receptor antagonists and therefore, may be used for the treatment of CCR-3 mediated diseases.
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| 申请公布号 |
CA2490148(A1) |
申请公布日期 |
2004.01.15 |
| 申请号 |
CA20032490148 |
申请日期 |
2003.06.25 |
| 申请人 |
F. HOFFMANN-LA ROCHE AG |
发明人 |
ROGERS, DANIEL HARRY;WILLIAMS, JOHN PATRICK;MAO, LONG;DU BOIS, DAISY JOE |
| 分类号 |
A61P11/06;C07D401/12;C07D401/14;C07D405/14;C07D409/14;(IPC1-7):C07D409/14;A61K31/506 |
主分类号 |
A61P11/06 |
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