发明名称 NOVEL Nogo RECEPTOR-LIKE POLYPEPTIDE AND DNA THEREOF
摘要 <p>A novel Nogo receptor-like polypeptide is found out as a protein showing elevated expression in the skeletal muscle of a Zucker fatty rat, which is a diabetes model rat, having a restricted diet and taking exercises. Moreover, a human homolog protein corresponding to it is found out. The above polypeptide is useful as a diabetic marker and a remedy for diabetes. Since this polypeptide is expressed most strongly in the cerebral cortex in the brain, it is also useful as a marker for neurodegenerative diseases such as Alzheimer's disease and a remedy for neurodegenerative diseases.</p>
申请公布号 WO2004005510(A1) 申请公布日期 2004.01.15
申请号 WO2003JP08469 申请日期 2003.07.03
申请人 SHIONOGI & CO., LTD.;ORITA, SATOSHI;SHIMAZAKI, ATSUYUKI;YANAGIMOTO, TORU;NAKAJIMA, MASATOSHI;OSHIMA, TAKEO 发明人 OSHIMA, TAKEO;ORITA, SATOSHI;SHIMAZAKI, ATSUYUKI;YANAGIMOTO, TORU;NAKAJIMA, MASATOSHI
分类号 A61K31/7088;A61K38/00;A61K48/00;A61P3/10;A61P21/04;A61P25/00;A61P25/16;A61P25/28;C07K14/705;G01N33/68;(IPC1-7):C12N15/09;A61K38/17;A61K39/395;A01K67/027;G01N33/566;G01N33/53;G01N33/50;G01N33/15;C12Q1/68;C12P21/02;C07K16/28;A61K31/708 主分类号 A61K31/7088
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