发明名称 Indazole compounds useful as protein kinase inhibitors
摘要 The present invention provides compounds of formula I: or a pharmaceutically acceptable derivative thereof, wherein R<1>, R<2>, V<1>, V<2>, and V<3 >are as described in the specification. These compounds are inhibitors of protein kinase, particularly inhibitors of AKT, PKA, PDK1, p70S6K, or ROCK kinase, mammalian protein kinases involved in proliferative and neurodegenerative disorders. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of utilizing those compositions in the treatment of various disorders.
申请公布号 US2004009968(A1) 申请公布日期 2004.01.15
申请号 US20030350806 申请日期 2003.01.23
申请人 BINCH HAYLEY;BRENCHLEY GUY;GOLEC JULIAN M. C.;KNEGTEL RONALD;MORTIMORE MICHAEL;PATEL SANJAY;RUTHERFORD ALISTAIR 发明人 BINCH HAYLEY;BRENCHLEY GUY;GOLEC JULIAN M. C.;KNEGTEL RONALD;MORTIMORE MICHAEL;PATEL SANJAY;RUTHERFORD ALISTAIR
分类号 A61K31/41;A61K31/416;A61K31/4178;A61K31/42;A61K31/422;A61K31/427;A61K31/4439;A61K31/496;A61K31/5377;A61K45/00;A61P1/16;A61P3/10;A61P7/00;A61P9/00;A61P9/04;A61P9/08;A61P9/10;A61P9/12;A61P11/06;A61P19/00;A61P19/10;A61P25/28;A61P29/00;A61P31/12;A61P31/18;A61P35/00;A61P37/02;A61P43/00;C07D231/56;C07D401/12;C07D403/12;C07D405/12;C07D409/12;C07D413/10;C07D413/12;C07D417/10;C07D417/12;(IPC1-7):A61K31/55;A61K31/541;A61K31/537;A61K31/53;A61K31/519;A61K31/502;A61K31/498;A61K31/474 主分类号 A61K31/41
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