<p>It is intended to provide a preventive or a remedy for diabetes which contains as the active ingredient a growth hormone secretagogue receptor (GHS-R) antagonist; a method of lowering blood glucose level characterized by comprising administering a GHS-R antagonist; a preventive or a remedy for obesity which contains as the active ingredient a GHS-R antagonist; and an appetite controlling agent which contains as the active ingredient a GHS-R antagonist.</p>
