发明名称 FATTY EMULSIONS CONTAINING REDUCING SUGAR AND METHOD FOR STERILIZING THE SAME
摘要 A fatty emulsion containing a reducing sugar, being an oil-in-water emulsion prepared by emulsifying fat or oil with an emulsifying agent wherein the aqueous phase contains both a reducing sugar and a buffer consisting of an organic acid exhibiting an acid dissociation constant of 5.0 to 7.5 in water or a salt thereof and the pH is adjusted to 5.0 to 7.5; a packaged fatty emulsion containing a reducing sugar, wherein a liquid medicine that contains a reducing sugar and fat or oil and that is sterilized in a state containing carbon dioxide dissolved therein is held in a plastic container for infusion fluid and the plastic container is held together with a carbon dioxide absorbent in a substantially oxygen-impermeable outer container; a process for the production of them; and a method for sterilizing the same. These fatty emulsions are suppressed in formation of free fatty acids and in decomposition of the sugar, thus being high-quality stable ones little causing discoloration.
申请公布号 EP0998935(B1) 申请公布日期 2004.01.14
申请号 EP19970933031 申请日期 1997.07.25
申请人 OTSUKA PHARMACEUTICAL FACTORY, INC. 发明人 KAWAKAMI, KEIICHI;WATANABE, KATSUSHI;NAKAI, TERU;UEI, KATSUMI;BANDOU, AYA;ISHII, TATSUYA;HIRATA, YUKI;FUJIMOTO, TAKASHI
分类号 A61J1/10;A23L1/30;A61J1/00;A61J1/05;A61J1/16;A61J1/20;A61K9/00;A61K9/107;A61K31/23;A61K31/70;A61K47/12;A61P3/00 主分类号 A61J1/10
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