发明名称 |
1H-INDAZOLE COMPOUNDS INHIBIT JNK |
摘要 |
<p>The present invention provides a novel 1H-indazole compound having an excellent JNK inhibitory action. More specifically, it provides a compound represented by the following formula, a salt thereof or a hydrate of them. <CHEM> Wherein R<1> is a C6-C14 aromatic cyclic hydrocarbon group etc.; R<2>, R<4> and R<5> each independently represent a hydrogen atom, a halogen atom, a cyano group etc.; L is a single bond, or a C1-C6 alkylene group etc.; X is a single bond, or a group represented by -CO-NH- or -NH-CO-, etc.; and Y is a C3-C8 cycloalkyl group, a C6-C14 aromatic cyclic hydrocarbon group or a 5- to 14-membered aromatic heterocyclic group etc.</p> |
申请公布号 |
EP1380576(A1) |
申请公布日期 |
2004.01.14 |
申请号 |
EP20020724612 |
申请日期 |
2002.04.15 |
申请人 |
EISAI CO., LTD. |
发明人 |
OINUMA, HITOSHI;OHI, NORIHITO;SATO, NOBUAKI;SOEJIMA, MOTOHIRO;SESHIMO, HIDENORI;TERAUCHI, TARO;DOKO, TAKASHI;KOHMURA, NAOHIRO |
分类号 |
A61P21/00;A61P25/00;A61P25/08;A61P25/14;A61P25/16;A61P25/28;A61P29/00;A61P37/00;A61P43/00;C07D231/56;(IPC1-7):C07D231/56;C07D401/04;C07D401/06;C07D401/12;C07D401/14;C07D403/04;C07D403/12;C07D405/04;C07D405/12;C07D405/14;C07D409/04;A61K31/416 |
主分类号 |
A61P21/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|