发明名称 Phenylethenyl or phenylethynyl derivatives functioning as glutamate receptor antagonists
摘要 <p>This invention relates to a compound and the use of the compound of the formula wherein R<SUP>1</SUP>, R<SUP>2</SUP>, R<SUP>3</SUP>, R<SUP>4 </SUP>and R<SUP>5 </SUP>are as defined in the description, A signifies -CH-CH- or -C≡C-; and B signifies wherein R<SUP>6 </SUP>to R<SUP>26</SUP>, X and Y are as defined in the specification or a pharmaceutically acceptable salt thereof, for use in pharmaceutical compositions for the treatment or prevention of mGluR5 receptor mediated disorders.</p>
申请公布号 CZ20031795(A3) 申请公布日期 2004.01.14
申请号 CZ20030001795 申请日期 2001.11.26
申请人 F. HOFFMANN-LA ROCHE AG 发明人 MUTEL VINCENT;PETERS JENS-UWE;WICHMANN JUERGEN
分类号 C07D233/64;A61K31/4045;A61K31/415;A61K31/4164;A61K31/4174;A61K31/4178;A61K31/4245;A61K31/437;A61K31/4985;A61P1/08;A61P9/02;A61P9/10;A61P13/02;A61P21/02;A61P25/00;A61P25/04;A61P25/06;A61P25/08;A61P25/14;A61P25/16;A61P25/18;A61P25/22;A61P25/24;A61P25/28;A61P25/34;A61P25/36;A61P31/18;A61P43/00;C07D209/14;C07D209/16;C07D231/12;C07D233/54;C07D233/58;C07D233/68;C07D233/90;C07D233/92;C07D233/94;C07D403/06;C07D403/10;C07D413/04;C07D491/147;C07D495/14;C07D498/04;C07D513/14;(IPC1-7):C07D233/90;A61K31/416 主分类号 C07D233/64
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