发明名称 |
СПОСОБ ХРОМАТОГРАФИЧЕСКОГО РАЗДЕЛЕНИЯ ПАКЛИТАКСЕЛА И ЦЕФАЛОМАННИНА |
摘要 |
A method for separating paclitaxel from cephalomannin and other related compounds by obtaining a starting material that contains paclitaxel and cephalomannin; dissolving the starting material in any one of a number of particularly defined solvents such as butyl formate and butyl acetate to form a mixture; subjecting the mixture to column chromatography to obtain an eluted fraction of paclitaxel, an eluted fraction of cephalomannin and a residue; and separately drying the paclitaxel and cephalomannin fractions to obtain separate crystalline forms of paclitaxel and cephalomannin, respectively. |
申请公布号 |
RU2002120482(A) |
申请公布日期 |
2004.01.10 |
申请号 |
RU20020120482 |
申请日期 |
2001.11.09 |
申请人 |
ИНДЕНА С.П.А. (IT) |
发明人 |
ГАБЕТТА Бруно (IT);ЦИНИ Джанфранко (IT) |
分类号 |
A61K31/337;A61P35/00;C07D305/14 |
主分类号 |
A61K31/337 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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