摘要 |
<P>PROBLEM TO BE SOLVED: To provide a disease marker for a cartilage disorder, a method of detecting the cartilage disorder using the disorder marker and a method for screening medicines useful for amelioration of the disorder. <P>SOLUTION: In the base sequence of the following genes: 5-HT7, EDG2, EDG1, ET(A), GPR88, PTH2R, VIP1R, CLIC2, SCN2A, ATA1, ABCA1, ABCG2, GAT1, PLTP, ENT1, NPT3 or IREG1, a polynucleotide having at least 15 continuous base pairs and/or a polynucleotide complementary to the polynucleotide are used as a disease marker for the cartilage disorder. <P>COPYRIGHT: (C)2004,JPO |