METHOD OF ANALYZING PROBE SUPPORT BY USING FLYING TIME SECONDARY ION MASS SPECTROMETRY

摘要

It is intended to provide a method of analyzing a measurement sample whereby the conditions of a probe located on a support and the occurrence/non-occurrence of the formation of a hybrid of the probe with a target nucleic acid (for example, imaging of the locations and quantitative analysis thereof) can be accurately analyzed. Namely, the conditions of a nucleic acid probe formed in a measurement sample in which a sample is reacted with a probe support and the occurrence/non-occurrence of the formation of a hybrid of the probe with a target nucleic acid are analyzed by the flying time secondary ion mass spectrometry in a state labeled with a label capable of forming a fragment ion which is not formed by the fragmentation of the probe and/or the target.