| 发明名称 |
INDUSTRIAL PROCESS FOR THE SYNTHESIS OF ISOBUTYL METHYL 1,4-DIHYDRO-2,6-DIMETHYL-4-(2-NITROPHENYL)-3,5-PYRIDINE DICARBOXYLATE (NISOLDIPINE) |
| 摘要 |
<p>Synthetic process of isobutyl methyl 1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)3,5-pyridine dicarboxylate (Nisoldipine) comprising on the reaction of isobutyl 2-(2-nitrobenzylidene)acetoacetate with methyl 3-aminocrotonate in an apolar solvent.</p> |
| 申请公布号 |
WO2004002958(A1) |
申请公布日期 |
2004.01.08 |
| 申请号 |
WO2003EP06755 |
申请日期 |
2003.06.26 |
| 申请人 |
ERREGIERRE, S.P.A.;FERRARI, MASSIMO;GHEZZI, MARCELLO;ALBERELLI, MANUEL;AMBROSINI, ALBERTO |
发明人 |
FERRARI, MASSIMO;GHEZZI, MARCELLO;ALBERELLI, MANUEL;AMBROSINI, ALBERTO |
| 分类号 |
C07D211/90;(IPC1-7):C07D211/90 |
主分类号 |
C07D211/90 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
