NOVEL METHOD OF STABILIZING DIAGNOSTIC AND THERAPEUTIC COMPOUNDS IN A CATIONIC CARRIER SYSTEM

摘要

The present invention relates to a method of stabilizing a low molecular weight compound in a cationic liposome, wherein said compound has a low solubility in a lipid membrane and/or a low permeability across a lipid membrane. Preferably, the compound is modified in order to increase lipid membrane solubility and/or lipid membrane permeability. After delivery of th e cationic liposome to a target site, particularly a target site in an organis m, the modification is reversed and the low molecular weight compound may enact its desired activity.