发明名称 |
VEGF-modulated genes and methods employing them |
摘要 |
The present invention provides methods for modulating angiogenesis and/or apoptosis comprising modulating the activity of at least one VEGF-modulated gene polypeptide. The invention also provides pharmaceutical compositions for modulating angiogenesis and apoptosis for the prevention or treatment of diseases associated with VEGF-modulated genes expression. The invention also provides diagnostic assays that use VEGF-modulated gene polynucleotides that hybridize with naturally occurring sequences encoding VEGF-modulated genes and antibodies that specifically bind to the protein. The invention also provides novel human and mouse arginine-rich proteins (ARPs) and nucleotide sequences. The invention provides for genetically engineered expression vectors and host cells comprising the nucleic acid sequence encoding ARPs and for a method for producing the protein
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申请公布号 |
US2004006780(A1) |
申请公布日期 |
2004.01.08 |
申请号 |
US20030428487 |
申请日期 |
2003.05.02 |
申请人 |
GERBER HANS-PETER;RASTELLI LUCA |
发明人 |
GERBER HANS-PETER;RASTELLI LUCA |
分类号 |
A01K67/027;A61K38/00;A61K39/395;A61K45/00;A61P9/00;A61P9/10;A61P35/00;A61P43/00;C07K14/47;C07K16/18;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/09;C12N15/12;C12Q1/02;C12Q1/48;C12Q1/68;(IPC1-7):A01K67/00;A61K38/18;C07K14/475;C07K16/22;C12P21/02;C12N5/06 |
主分类号 |
A01K67/027 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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