A SCREENING METHOD AND COMPOUNDS FOR TREATING FRIEDREICH ATAXIA

摘要

The present invention relates to a method for identifying and/or validating candidate substances for the treatment of Friedreich Ataxia (FRDA). Furthermore, the present invention relates to the use of selenium, Ebselen a nd Glutathione peroxidase (GPX) mimetics for the preparation of a medicament fo r the treatment of FRDA. Another aspect of the present invention relates to th e use of cells with reduced frataxin expression for identifying and/or validating candidate substances for the treatment of Friedreich Ataxia.