发明名称 LIPOPROTEIN FRACTION AND METHOD FOR IDENTIFYING ARTERIOSCLEROTIC DISEASE
摘要 PROBLEM TO BE SOLVED: To provide a material as a more accurate diagnostic marker as a risk factor for the onset of arteriosclerotic diseases. SOLUTION: A method for diagnosing an arteriosclerotic disease comprises the steps of injecting a blood sample into a sulfo-containing ion exchange column to adsorb lipoprotein in the presence of magnesium ion, eluting the weakly adsorbed lipoprotein with a solution containing a salt such as magnesium chloride, 100 mM or less in the concentration of other salts and 150-250 mM in the total salt concentration, further eluting the remaining lipoprotein with a solution containing a salt such as magnesium chloride, 100 mM or less in the concentration of other salts and 300-400 mM in the total salt concentration to obtain a lipoprotein fraction, measuring the cholesterol level of the fraction, and using the cholesterol level as a risk factor for the arteriosclerotic disease. COPYRIGHT: (C)2004,JPO
申请公布号 JP2004002322(A) 申请公布日期 2004.01.08
申请号 JP20030066401 申请日期 2003.03.12
申请人 TOSOH CORP 发明人 HIROWATARI YUJI;TADA NORIO;YOSHIDA HIROSHI
分类号 G01N33/92;C07K14/47;C07K14/775;G01N30/00;G01N30/88;(IPC1-7):C07K14/47 主分类号 G01N33/92
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