METHOD OF ATTACHMENT OF A BIOMOLECULE TO A SOLID SURFACE

摘要

Disclosed is a method for attaching biomolecules to a solid surface and a composition for preparing that surface for attachment. The composition comprises molecules of Formula I and Formula II which are defined as follows: Y - X - Z - R1 Formula I Y'- X' - Z' - R2 Formula II and wherein R1 is a biomolecule, a reactive group or a group capable of forming a reactive group; R2 is different to R1 and is present in at least a 10<4> fold molar excess to R1;Y and Y' are groups which can bind to a solid surface; X and X' are atoms which are, at least, bivalent; and Z and Z' are linker groups.