| 发明名称 |
MODIFIED MEK1 AND MEK2, CRYSTAL OF THE MEK1- OR MEK2-CONTAINING PEPTIDE/LIGAND/COFACTOR COMPLEX, AND METHOD OF USING THE SAME |
| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide the respective configurations of MEK1 peptide and MEK2 peptide, to provide the crystal of a MEK1 or MEK2 peptide/ligand/cofactor complex, to provide a method for producing the crystal, to provide three-dimensional structure information derived from the crystallographic data, and to provide a method of using the information. <P>SOLUTION: The MEK1 peptide and MEK2 peptide have modified amino acid sequences, respectively. <P>COPYRIGHT: (C)2004,JPO |
| 申请公布号 |
JP2004000135(A) |
申请公布日期 |
2004.01.08 |
| 申请号 |
JP20020372756 |
申请日期 |
2002.12.24 |
| 申请人 |
WARNER LAMBERT CO LLC |
发明人 |
OHREN JEFFREY FRANCIS;CHEN HUIFEN;DELANEY AMY MARIE;DUDLEY DAVID THOMAS;HASEMANN CHARLES ALBERT JR;KUFFA PETER;MCCONNELL PATRICK CHARLES;PAVLOVSKY ALEXANDER GREGORY;TECLE HAILE;WHITEHEAD CHRISTOPHER EMIL;YAN CHUNHONG;ZHANG ERLI |
| 分类号 |
C12N15/09;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N9/12;C12Q1/48;G06F17/50 |
主分类号 |
C12N15/09 |
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