发明名称 |
Pharmaceutical compositions |
摘要 |
This invention provides a microemulsion pre-concentrate comprising a difficultly soluble active agent and a carrier medium comprising 1) a hydrophilic phase which comprises dimethylisosorbide and/or a lower alkyl alkanoic ester, 2) a lipophilic phase, and 3) a surfactant. The active agent may be a cyclosporin or a macrolide. In another aspect, this invention provides a pharmaceutical composition for enteral or parenteral administration comprising a macrolide and an acid.
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申请公布号 |
US2004006012(A1) |
申请公布日期 |
2004.01.08 |
申请号 |
US20000738104 |
申请日期 |
2000.12.15 |
申请人 |
COTTENS SYLVAIN;HAEBERLIN BARBARA;SEDRAN RICHARD;VONDERSCHER JACKY |
发明人 |
COTTENS SYLVAIN;HAEBERLIN BARBARA;SEDRAN RICHARD;VONDERSCHER JACKY |
分类号 |
A61K9/00;A61K9/107;A61K9/48;A61K31/19;A61K31/4745;A61K38/13;(IPC1-7):A61K38/13;A61K31/474 |
主分类号 |
A61K9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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