发明名称 METHOD FOR THINNING OUTER LAYER OF KERNEL MOLDING AND POWDER GRANULE TO BE USED THEREFOR
摘要 PROBLEM TO BE SOLVED: To provide a method for thinning an outer layer of a kernel molding in a novel kernel locking system using a double pounder, and a powder granule in which the outer layer is more evidently thinned by the relevant method. SOLUTION: In the novel kernel locking system using the double pounder, a phenomenon of thinning the outer layer with a compressed pressure from the center of an inner core toward the outer layer is found out and the coarsest bulk density of the powder granule for the outer layer to be used is lowered. Preferably, the powder granule for the inner core is compressed at near a critical pressure so that the outer layer is thinned or a thin film outer layer molding is produced successfully. Further, as the powder granule suitable for the powder granule for the outer layer, namely, as the powder granule of the low bulk density keeping flowability, the powder granule mainly composed of hydroxypropylmethylcellulose whose compression rate is≤33% and whose coarsest bulk density is≤0.3g/mL and the powder granule mainly composed of sucrose whose compression rate is≤25% and whose coarsest bulk density is≤0.75g/mL are provided as well. COPYRIGHT: (C)2004,JPO
申请公布号 JP2004000575(A) 申请公布日期 2004.01.08
申请号 JP20030118004 申请日期 2003.04.23
申请人 SANWA KAGAKU KENKYUSHO CO LTD 发明人 OZEKI YUICHI
分类号 A61J3/10;A61K9/20;A61K47/38;B30B11/00;B30B11/34;(IPC1-7):A61J3/10 主分类号 A61J3/10
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